MRCP and FCPS Part 1 MCQ 47

A 15-year-old young boy with short stature, bony aches and pains, and learning difficulties comes to the clinic for review.

The most marked abnormality on examination is a short fifth digit on each hand.
Investigations reveal a calcium of 2.05 mmol/l (2.20-2.61), and a phosphate of 1.8 mmol/l (0.8-1.5).

Which of the following abnormalities is most likely to be present?

a) Alpha subunit G protein mutation
b) Beta subunit G protein mutation
c) Gamma subunit G protein mutation
d) Renal tubular disorder
e) Vitamin D receptor mutation

MRCP and FCPS Part 1 SBA Question 46

In the treatment of Migraine somatriptin is an example of

a) Betablocker
b) Alphablocker and a partial 5-HT2 agonist
c) Specific 5-HT1 agonist
d) 5-HT2 antagonist
e) TCA

FCPS & MRCP Part-1 MTF Questions | Myocardial blood flow #1

Myocardial blood flow to the left ventricle increases during:

(a) Early Systole
(b) Myocardial hypoxia
(c) Adenosine infusions
(d) Stimulation of sympathetic nerves to the heart
(e) Arterial hypertention

FCPS & MRCP Part-1 MTF Questions | Body fluid #1

Extracellular fluid differs from intracellular fluid in that is:

(a) Volume is greater
(b) Tonicity is lower
(c) Aninos are mainly inorganic
(d) Sodium:Potassium molar ratio is higher
(e) pH is lower

FCPS & MRCP Part-1 MTF Question | Bronchial asthma

Bronchial asthma is likely to be relieved by:

(a) Stimulation of cholinergic receptors
(b) Stimulation of beta adrenoceptors
(c) Histamin aerosols
(d) Drugs which stabilize mast cell membranes
(e) Glucocorticoids

FCPS & MRCP Part-1 MTF Question #27

Congenital Heart diseases with right to left shunt:

a) VSD
b) TOF
c) Tricuspid atresia
d) Hypoplasia of left ventricle
e) Ebstein's disease

FCPS & MRCP Part-1 MTF Question #26

Cardiac myocyte:

a) Structural syncytium
b) Rich in capillary than skeletal muscle
c) A-J junction
d) 80% mitochondria
e) Oxidative phosphorylation in source of energy

FCPS Part-1 MTF Question #25

In Case of haemodynamic effects of respiration:

a) JVP falls in inspiration
b) BP falls in expiration
c) HR accelerate during expiration
d) 2nd heart sound fuse with inspiration
e) Inspiration prolongs RV injection

MRCP Part 1 MCQ question #24

A young girl returns from a trip to India with a protracted history of watery diarrhoea.
Giardiasis is suspected but three stool samples are negative.
What is the best investigation to confirm Giardia as a diagnosis?

a) CT abdomen
b) Rectal biopsy
c) Serum IgM Giardia antibodies
d) Small intestine biopsy
e) Stool microscopy

Answer

MRCP Part 1 MCQ question #23

A 24 year old in-patient has chronic diarrhea as well as a large draining fistula. She complains of nausea and anorexia and of marked weakness. On physical examination her blood pressures is 120/80 mmHg. When she stands up, she feels very dizzy and her blood pressure is 110/70. Her heart rate is 100. She weighs 50 kg. When the intern pinches her forehead skin, it stands up like a tent. Her eyes are sunken. Her laboratory tests are pending. The intern suspects that she has extracellular fluid volume depletion. What volume of water would be expected in the extracellular compartment of a healthy 50 kg female?

a) 30 liters
b) 2.5 liters
c) 10 liters
d) 20 liters
e) 7.5 liters

Answer: