MRCP and FCPS Part 1 MCQ 47

A 15-year-old young boy with short stature, bony aches and pains, and learning difficulties comes to the clinic for review.

The most marked abnormality on examination is a short fifth digit on each hand.
Investigations reveal a calcium of 2.05 mmol/l (2.20-2.61), and a phosphate of 1.8 mmol/l (0.8-1.5).

Which of the following abnormalities is most likely to be present?

a) Alpha subunit G protein mutation
b) Beta subunit G protein mutation
c) Gamma subunit G protein mutation
d) Renal tubular disorder
e) Vitamin D receptor mutation

MRCP and FCPS Part 1 SBA Question 46

In the treatment of Migraine somatriptin is an example of

a) Betablocker
b) Alphablocker and a partial 5-HT2 agonist
c) Specific 5-HT1 agonist
d) 5-HT2 antagonist
e) TCA

FCPS and MRCP Part 1 SBA Question 45 | Microscopic Haematuria

A 26-year-old man is referred to the clinic with microscopic haematuria. He also has hypertension, which the GP diagnosed as essential hypertension and commenced him on amlodipine 5 mg daily.

You understand on further questioning that his brother has haematuria and renal impairment and his father died of a stroke at the age of 42. On examination his blood pressure is 152/88 mmHg, he has bilateral ballotable kidneys.

Investigations show:

Haemoglobin	13.4 g/dl	(13.5-18)
White cell count	6.0 x 109/l	(4-10)
Platelets	242 x 109/l	(150-400)
Sodium	140 mmol/l	(134-143)
Potassium	4.7 mmol/l	(3.5-5)
Creatinine	162 μ/l	(60-120)
Urine	Blood ++ Protein -

Which of the following is the investigation most appropriate to elucidate the underlying diagnosis?
(Please select 1 option)


 a) Contrast CT abdomen
 b) Cystoscopy
 c) Intravenous pyelogram (IVP)
 d) Plain abdominal film
 e) Ultrasound abdomen

FCPS & MRCP Part-1 MTF Questions | Myocardial blood flow #1

Myocardial blood flow to the left ventricle increases during:

(a) Early Systole
(b) Myocardial hypoxia
(c) Adenosine infusions
(d) Stimulation of sympathetic nerves to the heart
(e) Arterial hypertention

FCPS & MRCP Part-1 MTF Questions | Body fluid #1

Extracellular fluid differs from intracellular fluid in that is:

(a) Volume is greater
(b) Tonicity is lower
(c) Aninos are mainly inorganic
(d) Sodium:Potassium molar ratio is higher
(e) pH is lower

FCPS & MRCP Part-1 MTF Question | Bronchial asthma

Bronchial asthma is likely to be relieved by:

(a) Stimulation of cholinergic receptors
(b) Stimulation of beta adrenoceptors
(c) Histamin aerosols
(d) Drugs which stabilize mast cell membranes
(e) Glucocorticoids

FCPS & MRCP Part-1 MTF Question #27

Congenital Heart diseases with right to left shunt:

a) VSD
b) TOF
c) Tricuspid atresia
d) Hypoplasia of left ventricle
e) Ebstein's disease

FCPS & MRCP Part-1 MTF Question #26

Cardiac myocyte:

a) Structural syncytium
b) Rich in capillary than skeletal muscle
c) A-J junction
d) 80% mitochondria
e) Oxidative phosphorylation in source of energy

FCPS Part-1 MTF Question #25

In Case of haemodynamic effects of respiration:

a) JVP falls in inspiration
b) BP falls in expiration
c) HR accelerate during expiration
d) 2nd heart sound fuse with inspiration
e) Inspiration prolongs RV injection

MRCP Part 1 MCQ question #24

A young girl returns from a trip to India with a protracted history of watery diarrhoea.
Giardiasis is suspected but three stool samples are negative.
What is the best investigation to confirm Giardia as a diagnosis?

a) CT abdomen
b) Rectal biopsy
c) Serum IgM Giardia antibodies
d) Small intestine biopsy
e) Stool microscopy

Answer