MRCP and FCPS Part 1 MCQ 47

A 15-year-old young boy with short stature, bony aches and pains, and learning difficulties comes to the clinic for review.

The most marked abnormality on examination is a short fifth digit on each hand.
Investigations reveal a calcium of 2.05 mmol/l (2.20-2.61), and a phosphate of 1.8 mmol/l (0.8-1.5).

Which of the following abnormalities is most likely to be present?

a) Alpha subunit G protein mutation
b) Beta subunit G protein mutation
c) Gamma subunit G protein mutation
d) Renal tubular disorder
e) Vitamin D receptor mutation

MRCP and FCPS Part 1 SBA Question 46

In the treatment of Migraine somatriptin is an example of

a) Betablocker
b) Alphablocker and a partial 5-HT2 agonist
c) Specific 5-HT1 agonist
d) 5-HT2 antagonist
e) TCA