MRCP Part 1 MCQ question #24

A young girl returns from a trip to India with a protracted history of watery diarrhoea.
Giardiasis is suspected but three stool samples are negative.
What is the best investigation to confirm Giardia as a diagnosis?

a) CT abdomen
b) Rectal biopsy
c) Serum IgM Giardia antibodies
d) Small intestine biopsy
e) Stool microscopy

Answer

MRCP Part 1 MCQ question #23

A 24 year old in-patient has chronic diarrhea as well as a large draining fistula. She complains of nausea and anorexia and of marked weakness. On physical examination her blood pressures is 120/80 mmHg. When she stands up, she feels very dizzy and her blood pressure is 110/70. Her heart rate is 100. She weighs 50 kg. When the intern pinches her forehead skin, it stands up like a tent. Her eyes are sunken. Her laboratory tests are pending. The intern suspects that she has extracellular fluid volume depletion. What volume of water would be expected in the extracellular compartment of a healthy 50 kg female?

a) 30 liters
b) 2.5 liters
c) 10 liters
d) 20 liters
e) 7.5 liters

Answer:

MRCP Part 1 MCQ question #22

what is the main mode of action of beta-blockers in controlling hypertension ?

a) decrease cardiac input
b) slow the heart rate
c) increase the cardiac force of contraction
d) increase cardiac output
e) decrease plasma volume

Answer:

MRCP Part 1 MCQ question #21

Elderly woman develops sudden onset of a right sided partial ptosis and a divergent squint , there is no pupil asymmetry. When asked to raise both arms and she has weakness of the left arm in comparison with the right arm. The likely cause is :

a) pontine lesion
b) lesion at cerebellpontine angle
c) Weber's syndrome
d) mid-brain vascular lesion
e) diabetic third nerve palsy

Answer:

MRCP Part 1 MCQ question #24

A selective, reversible alpha-1 blocker which may be used in the pre-operative preparation of patients with phaeochromocytoma

a) phenylephrine
b) prazosin
c) clonidine
d) yohimbine
e) idazoxan

Answer:

MRCP Part 1 MCQ question #20

A 28 patient with a 10 year history of bronchial asthma presents with footdrop, he is noted to have purpura and painful skin nodules, the chest radiograph shows several peripheral nodules, these features are characteristic of:

a) Leoffler's syndrome
b) Idiopathic Hypereosinophilic Syndrome
c) chronic eosinophilic pneumonia
d) Churg-Strauss syndrome
e) Allergic bronchopulmonary aspergillosis

Answer:

MRCP Part 1 MCQ question #19

Muscarinic Acetylcholine receptors are selectively blocked by :

a) atropine
b) C5
c) muscarine
d) curare and C6
e) nicotine

Answer:

MRCP Part 1 MCQ question #18

An infarct involving the middle cerebellar peduncle is likely to be secondary to occlusion in the territory of the :

a) the Posterior Cerebral Artery
b) the Basilar Artery
c) The superior cerebellar artery
d) The anterior inferior cerebellar artery
e) The posterior inferior cerebellar artery

Answer:

MRCP Part 1 MCQ question #17

Aspirin inhibits platelet function by acetylating :

a) prostaglandin reductase
b) thromboxane synthetase
c) cyclooxygenase
d) succinic dehydrogenase
e) NADH-cytochrome-c-reductase

Answer:

MRCP Part 1 MCQ question #16

A carcinogen known to cause hepatocellular carcinoma

a) aniline dyes
b) Aflatoxins
c) Tamoxifen
d) Hydroquinone
e) asbestos

Answer: