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Wednesday, October 14, 2009

MRCOG Part 1 MTF #1

The antiphosphopholipid syndrome is associated with:

True / False

1. myocardial infarction

2. venous thrombosis

3. left ventricular thrombus

4. pulmonary hypertension

5. recurrent abortion

Answer:
1. T
2. T
3. T
4. T
5. T

Antiphospholipid syndrome is the association of arterial and venous thrombosis with antibodies directed against phospholipids. Originally noted as a complication in approximately 30% of patients with systemic lupus erythematosus, it is now also diagnosed in patients with thrombotic episodes and anti-phospholipid antibodies (aPL) but without clinical features of SLE - primary antiphospholipid syndrome. It is associated with MI, Recurrent miscarriages, DVT, Stroke, pulmonary hypertension (due to thromboembolic disease) and LV thrombus rarely reported. (Dr Bob Dalton) (Dr Shu Ho - d)