Marfan syndrome is associated with defective encoding of
a) collagen
b) elastin
c) fibrillin
d) elastin
e) laminin
Answer:
c) fibrillin
Explanation
Marfan syndrome is an autosomal dominant disorder that has been linked to the FBN1 gene on chromosome 15. FBN1 encodes a protein called fibrillin, which is essential for the formation of elastic fibres found in connective tissue.